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TRANSFORM WITH

Estrogen Vaginal Cream

Estrogen therapy in postmenopausal women can be beneficial by alleviating vaginal dryness and urinary symptoms.

✓
Improved sexual function
✓
Reduce dryness
✓
Reduce infections
✓
✓ Receive your medication in as little as 7 days**

from $95/mo.*

*with Membership, consult, and provider approval

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PROVIDER-SUPPORTED PROGRAMS
MEDICATION SHIPPED DISCREETLY TO YOUR DOOR
1:1 DOCTOR-LED CARE, EVERY QUARTER
ALL NECESSARY SUPPLIES ALWAYS FREE
BEST MEDICATION PRICES

The science behind
Estrogen Vaginal Cream

Vaginal estrogen cream benefits postmenopausal women by locally restoring estrogen to the vaginal and urinary tissues, relieving dryness, itching, and discomfort during sex, reducing painful urination and recurrent urinary tract infections, and improving overall vaginal health and comfort without significant systemic absorption or risks associated with oral hormone therapy.

The mechanism of
Estrogen Vaginal Cream

Vaginal estrogen cream benefits postmenopausal women by delivering low-dose estradiol (or equivalent estrogens) directly to urogenital tissues, where it binds to local estrogen receptors (primarily ERα and ERβ) in the vaginal epithelium, urethra, and bladder trigone to induce genomic and nongenomic effects. This promotes maturation and proliferation of vaginal epithelial cells, increasing glycogen-rich superficial layers that support Lactobacillus dominance, restores acidic vaginal pH (~4.5–5.5), enhances subepithelial vascularity and blood flow, thickens the epithelium, improves elasticity and lubrication, and reduces atrophy-related symptoms such as vaginal dryness, irritation, dyspareunia, and genitourinary syndrome of menopause (GSM). It also mitigates lower urinary tract symptoms by strengthening urethral closure pressure, decreasing urgency/frequency, and lowering recurrent urinary tract infection risk through microbiome stabilization and anti-inflammatory actions, all with minimal systemic absorption and thus negligible impact on serum estrogen levels or distant tissues.
INGREDIENTS
Estradiol
BENEFITS
Vaginal estrogen cream provides targeted relief for postmenopausal women by restoring moisture and elasticity to vaginal tissues, eliminating dryness and itching, making intercourse comfortable and enjoyable again, reducing painful urination and frequent urinary tract infections, and improving overall vaginal and urinary health and confidence—with very little estrogen entering the bloodstream, keeping systemic side effects minimal compared to oral forms.
  • ✔Improved sexual function
  • ✔Reduce dryness
Doctors Say:
A physician might choose estradiol vaginal cream over other products (such as non-hormonal vaginal moisturizers, lubricants, or oral alternatives) to alleviate vaginal dryness and other postmenopausal symptoms because it is the most effective first-line treatment for moderate to severe genitourinary syndrome of menopause (GSM), directly restoring vaginal epithelial thickness, elasticity, lubrication, and acidic pH through local activation of estrogen receptors, while also reducing urinary symptoms like urgency, frequency, and recurrent infections. Unlike moisturizers or lubricants, which provide only temporary symptom relief and do not address underlying atrophy, low-dose vaginal estradiol offers superior, sustained improvement in tissue health, dyspareunia, and overall comfort with minimal systemic absorption—resulting in negligible increases in blood estrogen levels and low risk of systemic side effects compared to oral hormone therapy. Major guidelines (e.g., from the North American Menopause Society and ACOG) recommend it as preferred for persistent or bothersome GSM when non-hormonal options fall short, making it a targeted, evidence-based choice for better long-term outcomes.
Profile
  • Initially daily, then moves to less frequent applications
  • Vaginal application
  • Dose varies per individual
60%
more affordable than our competitors.
Select the membership plan that suits your goals and lifestyle, and book your initial consultation.
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NAD+Med / IV Clinics
25mg injection$59 per shot$7 per shot*
1000mg (40 treatments)$2,360$249 (supplies included)**
Private At-Home UseNoYes
US FDA-Inspected PharmacyNoYes
*with Membership
**1000mg vial (40 × 25mg injections)
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“Before I got introduced to Vita Bella, I was obese, depressed, had no sex life, my business was in shambles, and honestly I struggled to wake up every day and live life. After Vita Bella, I got my dream body and found confidence I never even knew was there. I can’t keep the girls off of me, my confidence is through the roof, and my business has skyrocketed.”
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Transforming my health, one pound at a time with Vita Bella
“I’ve lost 35 pounds with Vita Bella, and it’s dramatically improved my lab results—my A1C dropped from 6.2 to 5.1, cholesterol went from 232 to 91, and triglycerides fell from 92 to 41, while my HDL rose from 36 to 63. It’s been a life-changing boost to my overall wellness!”
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*Disclaimer: "TRT or B12 Included In Program - No Additional Charge!" requires provider approval before starting treatment. Labs are required to verify eligibility and are not included in the membership. Program includes Testosterone Cypionate up to 200mg per week AND anastrozole either as a Cyp/Anastrozole blend or as anastrozole as an adjunct therapy up to 10 capsules per month. Program also includes Enclomiphene (up to 50mg daily), Clomiphene (up to 50mg daily), or B12 (up to 1000mcg weekly) as an alternative to Testosterone therapy. Program does not include Testosterone AND Enclomiphene, Clomiphene, or B12 together if prescribed in conjunction. Program does not include testosterone blends such as testosterone cypionate/ethanate/proprionate, testosterone creams, or gonadotropins such as HCG or gonadorelin. Program does not include any other medication. This program is subject to change at any time.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate.